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Article: Altered neuron excitability and synaptic plasticity in the cerebellar granular layer of juvenile prion protein knock-out mice with impaired motor control.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Prestori F; Rossi P; Bearzatto B; Lainé J; Necchi D; Diwakar S; Schiffmann SN; Axelrad H; D'Angelo E
J. Neurosci., 2008

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Cerebellum granule cell access resistance (MΩ) 21.2 ± 1.6 (22) 21.2 (MΩ) Data Table
Cerebellum granule cell cell capacitance (pF) 3.8 ± 0.2 (22) 3.8 (pF) Data Table
Cerebellum granule cell input resistance (GΩ) 1.9 ± 0.2 (22) 1900.0 (MΩ) Data Table
Cerebellum granule cell AHP amplitude (mV) 19.8 ± 1.8 (22) 19.8 (mV) Data Table
Cerebellum granule cell resting membrane potential (mV) -60.7 ± 2.8 (22) -60.7 (mV) Data Table
Cerebellum granule cell spike amplitude (mV) 53.6 ± 2.6 (22) 53.6 (mV) Data Table
Cerebellum granule cell spike half-width (ms) 1.2 ± 0.15 (22) 1.2 (ms) Data Table
Cerebellum granule cell spike threshold (mV) -42.7 ± 2.0 (22) -42.7 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
RecTemp 32.0
AnimalAge 17.0 - 22.0
Strain C57BL
PrepType in vitro
ElectrodeType Patch-clamp
Species Mice
ExternalSolution 5.0
InternalSolution 5.0
internal_1_pH 7.2
internal_1_Mg 5.0
internal_1_Na 4.0
internal_1_Cl 4.0
JxnPotential Unreported
Strain Other
internal_0_pH 7.2
internal_0_Mg 4.0
internal_0_Na 4.0
internal_0_K 126.0
internal_0_BAPTA 0.15
internal_0_ATP 3.0
internal_0_HEPES 5.0
internal_0_Cl 4.0
internal_0_Ca 0.05
internal_0_glucose 15.0
external_0_pH 7.4
external_0_Mg 1.2
external_0_Na 146.0
external_0_K 3.2
external_0_Cl 126.0
external_0_Ca 2.0
external_0_glucose 11.0
external_0_BIC 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
2049 Altered neuron excitability and synaptic plasticity in the cerebellar granular layer of juvenile prion protein knock-out mice with impaired motor control. Prestori F; Rossi P; Bearzatto B; Lainé J; Necchi D; Diwakar S; Schiffmann SN; Axelrad H; D'Angelo E J. Neurosci. 2008 False 5 Shreejoy Tripathy, 3
2048 Altered neuron excitability and synaptic plasticity in the cerebellar granular layer of juvenile prion protein knock-out mice with impaired motor control. Prestori F; Rossi P; Bearzatto B; Lainé J; Necchi D; Diwakar S; Schiffmann SN; Axelrad H; D'Angelo E J. Neurosci. 2008 False 3 Shreejoy Tripathy, 1
2050 Altered neuron excitability and synaptic plasticity in the cerebellar granular layer of juvenile prion protein knock-out mice with impaired motor control. Prestori F; Rossi P; Bearzatto B; Lainé J; Necchi D; Diwakar S; Schiffmann SN; Axelrad H; D'Angelo E J. Neurosci. 2008 False 0 None