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Article: Impaired inhibitory control of cortical synchronization in fragile X syndrome.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Paluszkiewicz SM; Olmos-Serrano JL; Corbin JG; Huntsman MM
J. Neurophysiol., 2011

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex Martinotti cell neocortex layer 2/3 low-threshold spiking inhibitory interneuron cell capacitance (pF) 92.1 ± 8.4 (16) 92.1 (pF) Data Table
Neocortex Martinotti cell neocortex layer 2/3 low-threshold spiking inhibitory interneuron input resistance (MΩ) 398.0 ± 23.0 (16) 398.0 (MΩ) Data Table
Neocortex Martinotti cell neocortex layer 2/3 low-threshold spiking inhibitory interneuron membrane time constant (ms) 36.4 ± 3.7 (16) 36.4 (ms) Data Table
Neocortex Martinotti cell neocortex layer 2/3 low-threshold spiking inhibitory interneuron resting membrane potential (mV) -54.5 ± 0.8 (16) -54.5 (mV) Data Table
Neocortex Martinotti cell neocortex layer 2/3 low-threshold spiking inhibitory interneuron rheobase (pA) 16.9 ± 2.4 (16) 16.9 (pA) Data Table
Neocortex Martinotti cell neocortex layer 2/3 low-threshold spiking inhibitory interneuron spike amplitude (mV) 64.0 ± 2.5 (16) 64.0 (mV) Data Table
Neocortex Martinotti cell neocortex layer 2/3 low-threshold spiking inhibitory interneuron spike half-width (ms) 1.98 ± 0.13 (16) 1.98 (ms) Data Table
Neocortex Martinotti cell neocortex layer 2/3 low-threshold spiking inhibitory interneuron spike rise time (ms) 1.37 ± 0.02 (16) 1.37 (ms) Data Table

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Metadata values

Experimental condition Value
Species Mice
ElectrodeType Patch-clamp
PrepType in vitro
RecTemp 23.0
AnimalAge 25.0 ± 1.0
ExternalSolution 5.0
InternalSolution 5.0
internal_1_Mg 6.0
internal_1_Na 0.3
internal_1_Cl 14.0
internal_1_K 140.0
JxnPotential Unreported
Strain Other
internal_0_Mg 6.0
internal_0_Na 0.3
internal_0_K 140.0
internal_0_GTP 0.3
internal_0_ATP 4.0
internal_0_EGTA 0.2
internal_0_HEPES 10.0
internal_0_Cl 14.0
external_0_Mg 2.0
external_0_Na 153.25
external_0_K 2.5
external_0_Cl 136.5
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
11767 Impaired inhibitory control of cortical synchronization in fragile X syndrome. Paluszkiewicz SM; Olmos-Serrano JL; Corbin JG; Huntsman MM J. Neurophysiol. 2011 False 8 Shreejoy Tripathy, Patrick Savage, 3