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Article: Cocaine self-administration enhances excitatory responses of pyramidal neurons in the rat medial prefrontal cortex to human immunodeficiency virus-1 Tat.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Wayman WN; Chen L; Napier TC; Hu XT Eur. J. Neurosci., 2015
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|---|---|---|---|---|
| Neocortex pyramidal cell layer 2-3 | dorsal prelimbic medial prefrontal cortex pyramidal neuron | input resistance (MΩ) | 116.5 ± 13.1 (9) | 116.5 (MΩ) | Data Table |
| Neocortex pyramidal cell layer 2-3 | dorsal prelimbic medial prefrontal cortex pyramidal neuron | resting membrane potential (mV) | -69.1 ± 1.0 (9) | -69.1 (mV) | Data Table |
| Neocortex pyramidal cell layer 2-3 | dorsal prelimbic medial prefrontal cortex pyramidal neuron | rheobase (pA) | 141.7 ± 17.2 (9) | 141.7 (pA) | Data Table |
| Neocortex pyramidal cell layer 2-3 | dorsal prelimbic medial prefrontal cortex pyramidal neuron | spike amplitude (mV) | 81.2 ± 6.0 (9) | 81.2 (mV) | Data Table |
| Neocortex pyramidal cell layer 2-3 | dorsal prelimbic medial prefrontal cortex pyramidal neuron | spike threshold (mV) | -40.0 ± 1.2 (9) | -40.0 (mV) | Data Table |
Metadata values
| Experimental condition | Value |
|---|---|
| Species | Rats |
| ElectrodeType | Patch-clamp |
| RecTemp | 34.0 |
| PrepType | in vitro |
| ExternalSolution | 5.0 |
| external_1_pH | 7.4 |
| external_1_Mg | 1.0 |
| external_1_Ca | 2.0 |
| external_1_Na | 151.25 |
| external_1_Cl | 133.5 |
| external_1_K | 2.5 |
| InternalSolution | 5.0 |
| Strain | Sprague-Dawley |
| JxnPotential | Unreported |
| AnimalWeight | 200.0 - 225.0 |
| internal_0_pH | 7.325 |
| internal_0_Mg | 2.0 |
| internal_0_Na | 6.3 |
| internal_0_K | 140.0 |
| internal_0_GTP | 0.3 |
| internal_0_ATP | 3.0 |
| internal_0_EGTA | 0.1 |
| internal_0_HEPES | 10.0 |
| internal_0_Cl | 24.0 |
| external_0_pH | 7.4 |
| external_0_Mg | 1.0 |
| external_0_Na | 151.25 |
| external_0_K | 2.5 |
| external_0_Cl | 133.5 |
| external_0_Ca | 2.0 |
| external_0_glucose | 15.0 |
Data table listing
| Data Table | Article Title | Authors | Journal | Year | Table needs expert? | Ephys table mentions | Curated by | Times validated |
|---|---|---|---|---|---|---|---|---|
| 45285 | Cocaine self-administration enhances excitatory responses of pyramidal neurons in the rat medial prefrontal cortex to human immunodeficiency virus-1 Tat. | Wayman WN; Chen L; Napier TC; Hu XT | Eur. J. Neurosci. | 2015 | False | 5 | Shreejoy Tripathy, Kerrie Tsigounis, | 1 |