Article: Acute optogenetic silencing of orexin/hypocretin neurons induces slow-wave sleep in mice.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Tsunematsu T; Kilduff TS; Boyden ES; Takahashi S; Tominaga M; Yamanaka A J. Neurosci., 2011
Halo (+) orexin neurons | EGFP (+) orexin neurons | |
---|---|---|
Resting membrane potential (mV) | −52.8 ± 2.1 (n = 5) | −52.5 ± 1.7 (n = 6) |
Peak amplitude (mV) | 17.3 ± 1.6 (n = 6) | 13.4 ± 3.0 (n = 5) |
Spontaneous firing (Hz) | 4.8 ± 1.0 (n = 5) | 4.7 ± 1.0 (n = 8) |
Input resistance (MΩ) | 531.2 ± 76.7 (n = 7) | 489.3 ± 30.2 (n = 12) |
Membrane capacitance (pF) | 27.1 ± 1.5 (n = 9) | 27.2 ± 2.0 (n = 11) |
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Values are means ± SEM.
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
---|---|---|---|---|---|
Other | lateral hypothalamic area halorhodopsin-expressing orexin-expressing neuron | input resistance (MΩ) | 531.2 ± 76.7 (7) | 531.2 (MΩ) | Data Table |
Other | Lateral hypothalamic area EGFP-expressing orexin-expressing neuron | input resistance (MΩ) | 489.3 ± 30.2 (12) | 489.3 (MΩ) | Data Table |
Other | lateral hypothalamic area halorhodopsin-expressing orexin-expressing neuron | cell capacitance (pF) | 27.1 ± 1.5 (9) | 27.1 (pF) | Data Table |
Other | Lateral hypothalamic area EGFP-expressing orexin-expressing neuron | cell capacitance (pF) | 27.2 ± 2.0 (11) | 27.2 (pF) | Data Table |
Other | lateral hypothalamic area halorhodopsin-expressing orexin-expressing neuron | resting membrane potential (mV) | -52.8 ± 2.1 (5) | -52.8 (mV) | Data Table |
Other | Lateral hypothalamic area EGFP-expressing orexin-expressing neuron | resting membrane potential (mV) | -52.5 ± 1.7 (6) | -52.5 (mV) | Data Table |
Other | lateral hypothalamic area halorhodopsin-expressing orexin-expressing neuron | spike peak (mV) | 17.3 ± 1.6 (6) | 17.3 (mV) | Data Table |
Other | Lateral hypothalamic area EGFP-expressing orexin-expressing neuron | spike peak (mV) | 13.4 ± 3.0 (5) | 13.4 (mV) | Data Table |
Other | lateral hypothalamic area halorhodopsin-expressing orexin-expressing neuron | spontaneous firing rate (Hz) | 4.8 ± 1.0 (5) | 4.8 (Hz) | Data Table |
Other | Lateral hypothalamic area EGFP-expressing orexin-expressing neuron | spontaneous firing rate (Hz) | 4.7 ± 1.0 (8) | 4.7 (Hz) | Data Table |