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Article: Stable mossy fiber long-term potentiation requires calcium influx at the granule cell soma, protein synthesis, and microtubule-dependent axonal transport.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Barnes SJ; Opitz T; Merkens M; Kelly T; von der Brelie C; Krueppel R; Beck H J. Neurosci., 2010
Effects of 25 μm nocodazole on passive and active properties of CA3 neurons in hippocampal slices
| Control | Nocodazole treated | |
|---|---|---|
| Rin (MΩ) | 164 ± 80 | 125 ± 47 |
| τ (ms) | 61 ± 21 | 56 ± 21 |
| Cm (pF) | 424 ± 209 | 403 ± 158 |
| Vm (mV) | −76 ± 5 | −78 ± 7 |
| AP peak (mV) | 26 ± 13 | 24 ± 10 |
| AP threshold (mV) | −58 ± 5 | −63 ± 4** |
| AP duration (ms) | 0.79 ± 0.21 | 0.77 ± 0.14 |
| Fast AHP (mV) | −64 ± 8.3 | −69 ± 3.7 |
| ADP (mV) | 6.0 ± 4.7 | 4.9 ± 2.4 |
| n | 12 | 13 |
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Data are presented as mean values ± SD and n values represent the number of CA3 cells from which data were obtained.
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↵**p < 0.01 compared to the respective control values paired using the paired Student's two-tailed t test. Rin, Input resistance; τ, membrane time constant; Cm, membrane capacitance; Vm, resting membrane potential; AP, action potential; AP duration, action potential duration at half-maximal amplitude; fast AHP, fast spike afterhyperpolarization; ADP, spike afterdepolarization.