Article: Electrophysiological and pharmacological properties of locomotor activity-related neurons in cfos-EGFP mice.
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Dai Y; Carlin KP; Li Z; McMahon DG; Brownstone RM; Jordan LM
J. Neurophysiol., 2009
Table 2.
5-HT-induced changes in cell membrane properties
|
|
|
Changes in Membrane Properties |
|
Control |
Mean |
|
|
|
Total |
EGFP+ |
Total |
EGFP+ |
↑Em Total
|
↓Em Total
|
n |
14 |
11 |
14 |
11 |
7 |
7 |
Em, mV
|
−72.3 ± 8 |
−72.9 ± 8 |
−1.3 ± 7 |
−0.8 ± 5 |
4.5 ± 3* |
−7.1 ± 3* |
Ith, pA
|
107.1 ± 61 |
118.2 ± 64 |
−3.6 ± 31 |
−4.5 ± 35 |
−7.1 ± 34 |
0.0 ± 29 |
Rin, MΩ
|
347.8 ± 111 |
342.5 ± 123 |
64.3 ± 90* |
71.5 ± 99* |
70.6 ± 54* |
58.0 ± 121 |
Vth, mV
|
−39.6 ± 10 |
−39.7 ± 11 |
−5.1 ± 6* |
−3.4 ± 4† |
−2.4 ± 4† |
−8.3 ± 6† |
AP height, mV |
43.5 ± 13 |
39.2 ± 11 |
−1.7 ± 11 |
−3.4 ± 11 |
−2.5 ± 13 |
−0.7 ± 9 |
AP width, ms |
3.8 ± 1 |
3.9 ± 1 |
0.6 ± 1† |
0.6 ± 1† |
0.4 ± 1 |
0.7 ± 1† |
AHP depth, mV |
16.4 ± 8 |
15.8 ± 8 |
−1.9 ± 3† |
−1.7 ± 3† |
−1.5 ± 4 |
−2.4 ± 2† |
AHP 1/2 decay, ms |
52.1 ± 43 |
46.3 ± 27 |
−8.7 ± 31 |
−5.6 ± 21 |
−17.9 ± 39 |
2 ± 13 |
Slope SS, Hz/nA |
88.3 ± 37 |
88.1 ± 39 |
−11.1 ± 37 |
−20.6 ± 27 |
−19.2 ± 29 |
−3.1 ± 47 |
Inferred neuron-electrophysiology data values