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Article: Target-specific output patterns are predicted by the distribution of regular-spiking and bursting pyramidal neurons in the subiculum.

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Kim Y; Spruston N
Hippocampus, 2012


Table 2. Subthreshold- and Suprathreshold Membrane Properties of Subicular Pyramidal Neurons
 BRSAmygLECOfCNAcITNMECRsCVHNPresub
  • *

    P < 0.05,

  • **

    P < 0.001; compared to B (t-test).

  • a

    Full width at half maximum amplitude.

% of bursting (n)(188)(218)15.2 (33)15.7 (51)18.0 (50)25.0 (64)57.4 (68)82.1 (28)75.0 (43)76.1 (46)91.3 (23)
Subthreshold
 Rin (MΩ)41.6 ± 0.960.8** ± 2.062.9 ± 4.452.3 ± 3.955.5 ± 4.552.6 ± 3.153.6 ± 3.247.5 ± 2.844.7 ± 2.345.9 ± 3.347.4 ± 5.5
 Sag ratio0.98 ± 0.071.56** ± 0.121.33 ± 0.161.72 ± 0.201.55 ± 0.131.67 ± 0.291.58 ± 0.151.55 ± 0.141.38 ± 0.091.24 ± 0.091.74 ± 0.14
 Vrest (mV)−69.7 ± 0.3−68.4 ± 0.3−69.5 ± 0.9−68.0 ± 0.6−68.4 ± 0.7−67.6 ± 0.5−69.5 ± 0.5−70.7 ± 0.6−69.3 ± 0.8−70.3 ± 0.5−68.7 ± 0.8
 N174201214549574434304622
Suprathreshold, at threshold
 Threshold (mV)−52.2 ± 0.3−50.5** ± 0.4−50.6 ± 0.8−49.0 ± 1.5−52.0 ± 0.5−48.8 ± 0.9−51.3 ± 0.5−51.7 ± 0.5−53.0 ± 0.4−52.7 ± 0.5−52.2 ± 1.2
 Amplitude (mV)93.0 ± 0.591.0** ± 0.791.6 ± 1.090.5 ± 2.694.5 ± 1.285.1 ± 2.690.6 ± 0.692.8 ± 0.994.2 ± 1.193.2 ± 0.893.0 ± 1.2
 Full width at half   maximum   amplitude (ms)0.66 ± 0.010.72** ± 0.010.83 ± 0.030.74 ± 0.020.77 ± 0.020.67 ± 0.010.64 ± 0.010.72 ± 0.020.57 ± 0.010.62 ± 0.010.68 ± 0.02
 Rise (dV/dt)367 ± 3341** ± 4331 ± 7345 ± 16349 ± 8327 ± 13359 ± 4356 ± 6379 ± 8374 ± 6354 ± 8
 Decay (dV/dt)−133 ± 2−118** ± 2−97 ± 3−109 ± 4−109 ± 4−118 ± 3−129 ± 2−121 ± 3−169 ± 4−141 ± 3−138 ± 5
 N147112211031156046174019
Suprathreshold, multiple spikes
 Threshold first   spike−53.0 ± 0.3−53.2 ± 0.5−53.4 ± 0.9−52.6 ± 2.4−54.5 ± 0.9−49.9 ± 1.1−52.8 ± 0.5−53.5 ± 0.6−54.5 ± 0.7−53.2 ± 0.6−52.2 ± 1.2
 Second spike−46.5 ± 0.4−42.7 ± 0.5−42.4 ± 1.0−42.7 ± 2.9−44.9 ± 1.0−42.0 ± 1.3−46.3 ± 0.5−46.4 ± 0.6−50.0 ± 0.8−47.7 ± 0.6−46.1 ± 1.4
 Amplitude first   spike89.3 ± 0.588.3 ± 0.789.2 ± 0.987.9 ± 2.991.8 ± 1.882.6 ± 2.287.5 ± 0.689.2 ± 0.890.8 ± 1.188.9 ± 0.992.0 ± 1.1
 Second spike72.7 ± 0.768.0** ± 1.160.7 ± 2.262.2 ± 5.267.4 ± 2.464.5 ± 2.471.8 ± 1.171.8 ± 1.477.1 ± 1.874.4 ± 1.473.9 ± 2.0
 FWHMAa first   spike0.66 ± 0.010.71** ± 0.010.81 ± 0.020.75 ± 0.020.76 ± 0.020.68 ± 0.020.64 ± 0.010.71 ± 0.020.58 ± 0.010.62 ± 0.010.68 ± 0.01
 Second spike0.92 ± 0.011.12** ± 0.031.43 ± 0.111.32 ± 0.111.16 ± 0.041.03 ± 0.030.92 ± 0.021.02 ± 0.040.77 ± 0.010.85 ± 0.020.94 ± 0.03
 Rise first spike351 ± 3331** ± 4328 ± 6333 ± 17338 ± 9315 ± 12345 ± 4342 ± 6362 ± 8355 ± 6342 ± 8
 Second spike232 ± 5176** ± 6124 ± 10142 ± 21172 ± 11173 ± 12220 ± 7215 ± 10265 ± 10242 ± 10221 ± 13
 Decay first spike−129 ± 2−115** ± 2−94 ± 3−103 ± 4−106 ± 4−111 ± 3−124 ± 2−118 ± 3−165 ± 4−134 ± 3−136 ± 5
 Second spike−69.4 ± 1.0−65.4* ± 1.6−54.0 ± 3.1−55.0 ± 3.7−57.8 ± 2.1−66.3 ± 2.9−70.5 ± 1.3−64.6 ± 1.8−82.3 ± 2.3−76.3 ± 1.7−69.0 ± 3.6
 ISI (ms)3.14 ± 0.553.94** ± 0.054.39 ± 0.114.20 ± 0.153.98 ± 0.133.74 ± 0.113.69 ± 0.091.96 ± 1.783.39 ± 0.063.76 ± 0.163.83 ± 0.15
 Norm I (%)184 ± 4219** ± 4245 ± 12214 ± 10219 ± 10196 ± 8187 ± 6196 ± 9194 ± 5176 ± 5211 ± 9
 n14310118827155744173919

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Subiculum pyramidal cell subiculum bursting pyramidal neuron spike max rise slope 367.0 ± 3.0 (188) 367.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum regular spiking pyramidal neuron spike max rise slope 341.0 ± 4.0 (218) 341.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to amygdala spike max rise slope 331.0 ± 7.0 (33) 331.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to lateral entorhinal cortex spike max rise slope 345.0 ± 16.0 (51) 345.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to orbitofrontal cortex spike max rise slope 349.0 ± 8.0 (50) 349.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to nucleus accumbens spike max rise slope 327.0 ± 13.0 (64) 327.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to thalamic nucleus spike max rise slope 359.0 ± 4.0 (68) 359.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to medial entorhinal cortex spike max rise slope 356.0 ± 6.0 (28) 356.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to retrosplenial cortex spike max rise slope 379.0 ± 8.0 (43) 379.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to ventromedial hypothalamus spike max rise slope 374.0 ± 6.0 (46) 374.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to presubiculum spike max rise slope 354.0 ± 8.0 (23) 354.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum bursting pyramidal neuron spike max decay slope -133.0 ± 2.0 (188) 133.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum regular spiking pyramidal neuron spike max decay slope -118.0 ± 2.0 (218) 118.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to amygdala spike max decay slope -97.0 ± 3.0 (33) 97.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to lateral entorhinal cortex spike max decay slope -109.0 ± 4.0 (51) 109.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to orbitofrontal cortex spike max decay slope -109.0 ± 4.0 (50) 109.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to nucleus accumbens spike max decay slope -118.0 ± 3.0 (64) 118.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to thalamic nucleus spike max decay slope -129.0 ± 2.0 (68) 129.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to medial entorhinal cortex spike max decay slope -121.0 ± 3.0 (28) 121.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to retrosplenial cortex spike max decay slope -169.0 ± 4.0 (43) 169.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to ventromedial hypothalamus spike max decay slope -141.0 ± 3.0 (46) 141.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to presubiculum spike max decay slope -138.0 ± 5.0 (23) 138.0 (mV/ms) Data Table
Subiculum pyramidal cell subiculum bursting pyramidal neuron input resistance (MΩ) 41.6 ± 0.9 (188) 41.6 (MΩ) Data Table
Subiculum pyramidal cell subiculum regular spiking pyramidal neuron input resistance (MΩ) 60.8 ± 2.0 (218) 60.8 (MΩ) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to amygdala input resistance (MΩ) 62.9 ± 4.4 (33) 62.9 (MΩ) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to lateral entorhinal cortex input resistance (MΩ) 52.3 ± 3.9 (51) 52.3 (MΩ) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to orbitofrontal cortex input resistance (MΩ) 55.5 ± 4.5 (50) 55.5 (MΩ) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to nucleus accumbens input resistance (MΩ) 52.6 ± 3.1 (64) 52.6 (MΩ) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to thalamic nucleus input resistance (MΩ) 53.6 ± 3.2 (68) 53.6 (MΩ) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to medial entorhinal cortex input resistance (MΩ) 47.5 ± 2.8 (28) 47.5 (MΩ) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to retrosplenial cortex input resistance (MΩ) 44.7 ± 2.3 (43) 44.7 (MΩ) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to ventromedial hypothalamus input resistance (MΩ) 45.9 ± 3.3 (46) 45.9 (MΩ) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to presubiculum input resistance (MΩ) 47.4 ± 5.5 (23) 47.4 (MΩ) Data Table
Subiculum pyramidal cell subiculum bursting pyramidal neuron sag ratio 0.98 ± 0.07 (188) 1.02040816327 (ratio) Data Table
Subiculum pyramidal cell subiculum regular spiking pyramidal neuron sag ratio 1.56 ± 0.12 (218) 0.641025641026 (ratio) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to amygdala sag ratio 1.33 ± 0.16 (33) 1.33 (ratio) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to lateral entorhinal cortex sag ratio 1.72 ± 0.2 (51) 1.72 (ratio) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to orbitofrontal cortex sag ratio 1.55 ± 0.13 (50) 1.55 (ratio) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to nucleus accumbens sag ratio 1.67 ± 0.29 (64) 1.67 (ratio) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to thalamic nucleus sag ratio 1.58 ± 0.15 (68) 1.58 (ratio) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to medial entorhinal cortex sag ratio 1.55 ± 0.14 (28) 1.55 (ratio) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to retrosplenial cortex sag ratio 1.38 ± 0.09 (43) 1.38 (ratio) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to ventromedial hypothalamus sag ratio 1.24 ± 0.09 (46) 1.24 (ratio) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to presubiculum sag ratio 1.74 ± 0.14 (23) 1.74 (ratio) Data Table
Subiculum pyramidal cell subiculum bursting pyramidal neuron resting membrane potential (mV) -69.7 ± 0.3 (188) -69.7 (mV) Data Table
Subiculum pyramidal cell subiculum regular spiking pyramidal neuron resting membrane potential (mV) -68.4 ± 0.3 (218) -68.4 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to amygdala resting membrane potential (mV) -69.5 ± 0.9 (33) -69.5 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to lateral entorhinal cortex resting membrane potential (mV) -68.0 ± 0.6 (51) -68.0 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to orbitofrontal cortex resting membrane potential (mV) -68.4 ± 0.7 (50) -68.4 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to nucleus accumbens resting membrane potential (mV) -67.6 ± 0.5 (64) -67.6 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to thalamic nucleus resting membrane potential (mV) -69.5 ± 0.5 (68) -69.5 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to medial entorhinal cortex resting membrane potential (mV) -70.7 ± 0.6 (28) -70.7 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to retrosplenial cortex resting membrane potential (mV) -69.3 ± 0.8 (43) -69.3 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to ventromedial hypothalamus resting membrane potential (mV) -70.3 ± 0.5 (46) -70.3 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to presubiculum resting membrane potential (mV) -68.7 ± 0.8 (23) -68.7 (mV) Data Table
Subiculum pyramidal cell subiculum bursting pyramidal neuron spike threshold (mV) -52.2 ± 0.3 (188) -52.2 (mV) Data Table
Subiculum pyramidal cell subiculum regular spiking pyramidal neuron spike threshold (mV) -50.5 ± 0.4 (218) -50.5 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to amygdala spike threshold (mV) -50.6 ± 0.8 (33) -50.6 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to lateral entorhinal cortex spike threshold (mV) -49.0 ± 1.5 (51) -49.0 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to orbitofrontal cortex spike threshold (mV) -52.0 ± 0.5 (50) -52.0 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to nucleus accumbens spike threshold (mV) -48.8 ± 0.9 (64) -48.8 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to thalamic nucleus spike threshold (mV) -51.3 ± 0.5 (68) -51.3 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to medial entorhinal cortex spike threshold (mV) -51.7 ± 0.5 (28) -51.7 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to retrosplenial cortex spike threshold (mV) -53.0 ± 0.4 (43) -53.0 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to ventromedial hypothalamus spike threshold (mV) -52.7 ± 0.5 (46) -52.7 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to presubiculum spike threshold (mV) -52.2 ± 1.2 (23) -52.2 (mV) Data Table
Subiculum pyramidal cell subiculum bursting pyramidal neuron spike amplitude from resting (mV) 93.0 ± 0.5 (188) 75.3 (mV) Data Table
Subiculum pyramidal cell subiculum regular spiking pyramidal neuron spike amplitude from resting (mV) 91.0 ± 0.7 (218) 73.3 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to amygdala spike amplitude from resting (mV) 91.6 ± 1.0 (33) 91.6 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to lateral entorhinal cortex spike amplitude from resting (mV) 90.5 ± 2.6 (51) 90.5 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to orbitofrontal cortex spike amplitude from resting (mV) 94.5 ± 1.2 (50) 94.5 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to nucleus accumbens spike amplitude from resting (mV) 85.1 ± 2.6 (64) 85.1 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to thalamic nucleus spike amplitude from resting (mV) 90.6 ± 0.6 (68) 90.6 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to medial entorhinal cortex spike amplitude from resting (mV) 92.8 ± 0.9 (28) 92.8 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to retrosplenial cortex spike amplitude from resting (mV) 94.2 ± 1.1 (43) 94.2 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to ventromedial hypothalamus spike amplitude from resting (mV) 93.2 ± 0.8 (46) 93.2 (mV) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to presubiculum spike amplitude from resting (mV) 93.0 ± 1.2 (23) 93.0 (mV) Data Table
Subiculum pyramidal cell subiculum bursting pyramidal neuron spike half-width (ms) 0.66 ± 0.01 (188) 0.66 (ms) Data Table
Subiculum pyramidal cell subiculum regular spiking pyramidal neuron spike half-width (ms) 0.72 ± 0.01 (218) 0.72 (ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to amygdala spike half-width (ms) 0.83 ± 0.03 (33) 0.83 (ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to lateral entorhinal cortex spike half-width (ms) 0.74 ± 0.02 (51) 0.74 (ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to orbitofrontal cortex spike half-width (ms) 0.77 ± 0.02 (50) 0.77 (ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to nucleus accumbens spike half-width (ms) 0.67 ± 0.01 (64) 0.67 (ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to thalamic nucleus spike half-width (ms) 0.64 ± 0.01 (68) 0.64 (ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to medial entorhinal cortex spike half-width (ms) 0.72 ± 0.02 (28) 0.72 (ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to retrosplenial cortex spike half-width (ms) 0.57 ± 0.01 (43) 0.57 (ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to ventromedial hypothalamus spike half-width (ms) 0.62 ± 0.01 (46) 0.62 (ms) Data Table
Subiculum pyramidal cell subiculum pyramidal neuron projecting to presubiculum spike half-width (ms) 0.68 ± 0.02 (23) 0.68 (ms) Data Table