AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Intrinsic neuronal excitability is reversibly altered by a single experience in fear conditioning.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
McKay BM; Matthews EA; Oliveira FA; Disterhoft JF
J. Neurophysiol., 2009


Table 1.

Intrinsic properties of cells included in this study

Cohort/Group Number of Cells, n Vrest, mV Vthresh, mV Sag, mV Rinput, MΩ
Trained
    Paired 20 −65.2 ± 0.8 −42.9 ± 2.6 −3.7 ± 0.2 72.1 ± 4.5
    Shock 19 −65.2 ± 1.0 −39.4 ± 2.7 −3.3 ± 0.3 88.6 ± 3.9*
    Tone 26 −66.8 ± 0.7 −43.7 ± 2.4 −4.1 ± 0.3 78.0 ± 4.9
    Naïve 19 −67.0 ± 0.6 −45.6 ± 1.5 −3.8 ± 0.2 70.9 ± 4.8
Extinguished 20 −64.3 ± 0.8 −35.1 ± 4.4** −3.8 ± 0.3 80.7 ± 5.6
Tested
    Paired 22 −64.3 ± 0.7 −45.8 ± 1.4 −3.5 ± 0.3 71.0 ± 5.0
    Shock 22 −65.0 ± 0.5 −42.6 ± 2.0 −3.5 ± 0.3 67.8 ± 5.0
    Tone 19 −65.2 ± 0.9 −41.3 ± 1.5 −4.3 ± 0.3 78.3 ± 3.3

  • Values are means ± SE. Resting potential (Vrest), action potential threshold (Vthresh), and input resistance (Rinput) were measured for every cell. Vrest was calculated as the potential with 0-pA current current injection; Vthresh was calculated as the voltage where the first derivative of the action potential equaled 20 mV/ms; Rinput was calculated as the slope of the I–V curve generated with an 800-ms current injection from −0.3 to +0.1 nA; Sag was measured as the difference between the peak and steady-state hyperpolarization in response to an 800-ms, −300-PA current step.

  • ↵* = F(7,159) = 1.98, P = 0.062;

  • ↵* = F(7,159) = 1.85, P = 0.081.


Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -67.0 ± 0.6 (19) -67.0 (mV) Data Table
Hippocampus CA1 pyramidal cell spike threshold (mV) -45.6 ± 1.5 (19) -45.6 (mV) Data Table
Hippocampus CA1 pyramidal cell sag amplitude (mV) -3.8 ± 0.2 (19) -3.8 (mV) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 70.9 ± 4.8 (19) 70.9 (MΩ) Data Table