Article: Hyperexcitability of distal dendrites in hippocampal pyramidal cells after chronic partial deafferentation.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Cai X; Wei DS; Gallagher SE; Bagal A; Mei YA; Kao JP; Thompson SM; Tang CM J. Neurosci., 2007
Unlesioned | Lesioned | |
---|---|---|
Input resistance (MΩ) | 111 ± 31 (23) | 157 ± 50 (25) |
Action potential amplitude (mV) | 82.6 ± 2.4 (23) | 82.8 ± 1.6 (17) |
Action potential rise time (ms) | 0.67 ± 0.05 (23) | 0.62 ± 0.03 (17) |
Action potential threshold (mV) | −37.9 ± 1.2 (23) | −41.7 ± 1.5 (17) |
Action potential latency (ms) | 313.9 ± 35.9 (21) | 372 ± 64.8 (13) |
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The number of observations is given in parentheses. Input resistance was determined from the voltage deflection produced by 150 ms, −50 pA current pulses. Action potential parameters were determined from just suprathreshold responses to 500 ms depolarizing current pulses. Latency was determined for the smallest amplitude 500 ms depolarizing current pulse eliciting an action potential. There were no significant differences in any parameter between lesioned and unlesioned cultures.
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
---|---|---|---|---|---|
Hippocampus CA1 pyramidal cell | input resistance (MΩ) | 111.0 ± 31.0 (23) | 111.0 (MΩ) | Data Table | |
Hippocampus CA1 pyramidal cell | spike amplitude (mV) | 82.6 ± 2.4 (23) | 82.6 (mV) | Data Table | |
Hippocampus CA1 pyramidal cell | spike rise time (ms) | 0.67 ± 0.05 (23) | 0.67 (ms) | Data Table | |
Hippocampus CA1 pyramidal cell | spike threshold (mV) | -37.9 ± 1.2 (23) | -37.9 (mV) | Data Table | |
Hippocampus CA1 pyramidal cell | first spike latency (ms) | 313.9 ± 35.9 (21) | 313.9 (ms) | Data Table |