Article: Role of olivary electrical coupling in cerebellar motor learning.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Van Der Giessen RS; Koekkoek SK; van Dorp S; De Gruijl JR; Cupido A; Khosrovani S; Dortland B; Wellershaus K; Degen J; Deuchars J; Fuchs EC; Monyer H; Willecke K; De Jeu MT; De Zeeuw CI Neuron, 2008
Table 1Properties of Olivary Neurons in Wild-Type and Cx36−/− Mutants following Whole-Cell Recordings In Vivo (Values Indicate Mean ± SEM)
Statistics: t test or χ2 test. ∗All measured subthreshold oscillations (STOs); a single cell can have multiple STO frequencies.
Parameter | Wild-Type | n | Cx36−/− | n | Statistics |
Cells Expressing Spontaneous STOs | |||||
Resting membrane potential (mV) | −55 ± 1 | 53 | −55 ± 1 | 16 | 0.31 |
Input resistance (MΩ) | 40.1 ± 3.8 | 53 | 45.2 ± 4.3 | 14 | 0.24 |
Membrane capacitance (pF) | 188.7 ± 11.8 | 53 | 233.0 ± 37.0 | 14 | 0.07 |
Firing rate (Hz) | 0.64 ± 0.05 | 50 | 0.54 ± 0.09 | 14 | 0.15 |
Coefficient of variation for spike intervals | 0.72 ± 0.02 | 50 | 0.83 ± 0.05 | 14 | 0.02 |
STO frequency (Hz) | 3.1 ± 0.3∗ | 53 | 3.4 ± 0.6∗ | 16 | 0.32 |
STO amplitude (mV) | 8 ± 1∗ | 53 | 8 ± 1∗ | 16 | 0.44 |
% Cells expressing depolarizing sag | 24 | 58 | 62 | 14 | 0.01 |
% Cells expressing rebound depolarization | 62 | 58 | 92 | 14 | 0.05 |
% Cells expressing afterhyperpolarization | 19 | 45 | 45 | 12 | 0.26 |
Cells Expressing No Spontaneous STOs | |||||
Resting membrane potential (mV) | −52 ± 2 | 9 | −58 ± 1 | 12 | 0.11 |
Input resistance (MΩ) | 42.3 ± 5.2 | 9 | 48.3 ± 15.5 | 12 | 0.32 |
Membrane capacitance (pF) | 159.6 ± 19.1 | 9 | 100.6 ± 3.9 | 12 | 0.07 |
Firing rate (Hz) | 0.54 ± 0.11 | 9 | 0.92 ± 0.35 | 12 | 0.10 |
Coefficient of variation for spike intervals | 0.68 ± 0.13 | 9 | 0.68 ± 0.04 | 12 | 0.49 |
% Cells expressing depolarizing sag | 0 | 8 | 0 | 12 | 1.00 |
% Cells expressing rebound depolarization | 60 | 8 | 100 | 12 | 0.29 |
% Cells expressing afterhyperpolarization | 40 | 8 | 0 | 12 | 0.29 |