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Article: Focal deletion of the adenosine A1 receptor in adult mice using an adeno-associated viral vector.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Scammell TE; Arrigoni E; Thompson MA; Ronan PJ; Saper CB; Greene RW J. Neurosci., 2003
Table 1.
Electrophysiologic characteristics are unaltered in CA1 pyramidal neurons lacking A1 receptors (n = 5)
| Control neurons | Neurons lacking A1R response | |
|---|---|---|
| Vm (μV) | -70.7 ± 1.8 | -69.0 ± 2.4 |
| Rm (mΩ) | 143.1 ± 16.3 | 135.8 ± 25.9 |
| AP threshold (μV) | -50.4 ± 1.3 | -51.7 ± 1.2 |
| AP peak (μV) | 42.5 ± 2.7 | 45.1 ± 1.4 |
| AP half width (msec) | 1.2 ± 0.1 | 1.1 ± 0.1 |
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Control neurons were contralateral to the AAV-Cre injection site or from uninjected mice (n = 7). Values are means ± SE. Vm, Membrane potential; Rm, membrane resistance; AP, action potential.
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|---|---|---|---|---|
| Hippocampus CA1 pyramidal cell | spike peak (μV) | 42.5 ± 2.7 (7) | 0.0425 (mV) | Data Table | |
| Hippocampus CA1 pyramidal cell | spike half-width (msec) | 1.2 ± 0.1 (7) | 1.2 (ms) | Data Table | |
| Hippocampus CA1 pyramidal cell | resting membrane potential (μV) | -70.7 ± 1.8 (7) | -70.7 (mV) | Data Table | |
| Hippocampus CA1 pyramidal cell | input resistance (mΩ) | 143.1 ± 16.3 (7) | 143.1 (MΩ) | Data Table | |
| Hippocampus CA1 pyramidal cell | spike threshold (μV) | -50.4 ± 1.3 (7) | -- | Data Table |