Article: Cortical slow oscillatory activity is reflected in the membrane potential and spike trains of striatal neurons in rats with chronic nigrostriatal lesions.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Tseng KY; Kasanetz F; Kargieman L; Riquelme LA; Murer MG J. Neurosci., 2001
Control | 6-OHDA | |
---|---|---|
Number of silent neurons | 131-a | 4 |
Number of neurons firing spontaneously | 14 | 27 |
Action potential amplitude (mV)1-b | 50.3 ± 1.8 | 50.9 ± 0.9 |
Action potential duration (msec)1-c | 0.85 ± 0.03 | 0.81 ± 0.03 |
Threshold (spontaneous firing) (mV)1-d | −54.8 ± 1.0 | −54.5 ± 0.8 |
Input resistance (MΩ)1-e | 53.0 ± 3.3 | 51.9 ± 4.7 |
Silent neurons | ||
Voltage in the down state (mV) | −87.4 ± 3.5 | −87.4 ± 4.3 |
Voltage in the up state (mV) | −77.5 ± 3.8 | −76.8 ± 4.7 |
Spontaneously active neurons | ||
Voltage in the down state (mV) | −82.4 ± 3.1 | −73.3 ± 1.81-f |
Voltage in the up state (mV) | −69.7 ± 2.1 | −63.1 ± 1.31-g |
Duration of the recordings (minutes, mean ± SEM, and range)1-h | 49 ± 8 (11–179) | 51 ± 9 (11–208) |
-
Data are mean ± SEM. Spike measures were taken from spontaneously active neurons.
-
↵F1-a p = 0.004 Fisher exact probability test.
-
↵F1-b Measured from threshold.
-
↵F1-c Measured at half maximal amplitude.
-
↵F1-d Defined as the membrane potential at which the rate of voltage change exceeded 4 V/sec (Wickens and Wilson, 1998).
-
↵F1-e Measured by applying depolarizing current pulses during the down state.
-
↵F1-f p = 0.012, two-tailed Student's t test.
-
↵F1-g p = 0.046, two-tailed Student's t test.
-
↵F1-h Includes the time spent in the application of Neurobiotin.
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
---|---|---|---|---|---|
Other | Neostriatum neuron | spike half-width (msec) | 0.85 ± 0.03 (14) | 0.85 (ms) | Data Table |
Other | Neostriatum neuron | spike threshold | -54.8 ± 1.0 (14) | -54.8 (mV) | Data Table |
Other | Neostriatum neuron | input resistance (MΩ) | 53.0 ± 3.3 (14) | 53.0 (MΩ) | Data Table |
Other | Neostriatum neuron | spike amplitude (mV) | 50.3 ± 1.8 (14) | 50.3 (mV) | Data Table |