n | Diameter, μm | Cm, pF | Vm, mV | Rin, MΩ | AP Rheobase, pA | AP VTH, mV | AP Amplitude, mV | AP Duration, ms | MS/non-MS | |
---|---|---|---|---|---|---|---|---|---|---|
Control | 9 | 38.9 ± 2.1 | 48.9 ± 5.3 | −61.2 ± 2.0 | 108.9 ± 19.9 | 627.8 ± 43.4 | −26.2 ± 6.7 | 115.4 ± 7.7 | 1.5 ± 0.3 | 0/9 |
CCD | 8 | 40.8 ± 1.4 | 52.7 ± 3.5 | −58.9 ± 1.7 | 125.9 ± 19.6 | 456.3 ± 78.7* | −35.1 ± 3.2 | 109.1 ± 7.8 | 1.2 ± 0.2 | 3/5 |
-
Values are mean ± SE. CCD, chronic compression; n, number of cells; Cm, cell capacitance; Vm, membrane potential; Rin, input resistance; AP, action potential; AP Rheobase, current threshold of AP; VTH, voltage threshold; MS, number of cells firing multiple (≥2) spikes to current step at 2× rheobase; non-MS, number of cells discharging 1 spike.
-
↵* P < 0.05 (Student's t-tests, significant differences between control and CCD).