Table 1.
Electrophysiological properties of GABAergic and non-GABAergic MePV cellsa
| Non-GABAergic (n = 79) | GABAergic (n = 75) | p | |
|---|---|---|---|
| Vrest (mV) | -68 ± 1 | -65 ± 1 | <0.001 |
| Rin (MΩ) | 234 ± 8 | 242 ± 10 | NS |
| τm (ms) | 20 ± 1 | 14 ± 1 | <0.0001 |
| sag ratio | 1 ± 0.003 | 0.9 ± 0.005 | <0.0001 |
| Rheobase (pA) | 90 ± 4 | 101 ± 6 | NS |
| AP threshold (mV) | -32 ± 0.5 | -35 ± 1 | <0.01 |
| AP latency (ms) | 116 ± 15 | 134 ± 18 | NS |
| AP amplitude (mV) | 76 ± 1 | 69 ± 1 | <0.001 |
| AP HW (ms) | 0.7 ± 0.01 | 0.6 ± 0.01 | <0.01 |
| fAHP amp (mV) | 20 ± 0.4 | 20 ± 0.5 | NS |
| fAHP latency (ms) | 2.2 ± 0.1 | 1.9 ± 0.1 | <0.01 |
| mAHP amp (mV) | 18 ± 0.4 | 16 ± 1 | <0.05 |
| mAHP latency (ms) | 21 ± 1 | 14 ± 1 | <0.0001 |
| AP broadening | 0.2 ± 0.02 | 0.3 ± 0.03 | <0.05 |
| AP amplitude accommodation | 0.1 ± 0.01 | 0.2 ± 0.02 | <0.01 |
| Firing frequency accommodation | 4 ± 0.4 | 1 ± 0.2 | <0.0001 |
| Maximal firing frequency (Hz) | 50 ± 2 | 70 ± 4 | <0.0001 |
-
↵aData are mean ± SEM. Definition of electrophysiological properties is explained in Materials and Methods. Unpaired Student's t test was used for statistical comparison. Statistical significance was defined as p < 0.05. n, number of cells; NS, Not significant.