Table 1.
Membrane and neurochemical properties of IS-3 versus BC
BC | IS3 | |
---|---|---|
Resting membrane potential (mV) | -63.55 ± 1.6* (n = 10) | -74.2 ± 0.7 (n = 9) |
Input resistance (MΩ) | 251.4 ± 50.1*** (n = 10) | 496.9 ± 28.6 (n = 46) |
Membrane capacitance (pF) | 49.7 ± 4.7* (n = 10) | 38.5 ± 2 (n = 45) |
Rheobase (pA) | 70 ± 11.3 (n = 6) | 42.8 ± 8 (n = 23) |
AP threshold (mV) | -43.25 ± 2.4 (n = 6) | -44.6 ± 1.4 (n = 23) |
AP amplitude (mV) | 80.4 ± 6.1 (n = 6) | 86.3 ± 2.2 (n = 23) |
AP duration (ms) | 1.02 ± 0.05 (n = 6) | 1.1 ± 0.06 (n = 23) |
Ratio of the last and first interspike intervals | 4.05 ± 0.4 (n = 6) | 3.16 ± 0.9 (n = 8) |
Maximal firing frequency (Hz) | 156 ± 17 (n = 6) | 171 ± 17 (n = 8) |
Calretinin | - | + |
Somatostatin | - | - |
Muscarinic receptor 2 | NT | - |
Cholecystokinin | + | - |
Neuropeptide Y | - | - |