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Article: Specific Early and Late Oddball-Evoked Responses in Excitatory and Inhibitory Neurons of Mouse Auditory Cortex.

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Chen IW; Helmchen F; Lütcke H
J. Neurosci., 2015


Table 1.

Electrophysiological properties of pyramidal neurons, and SST and PV interneurons in L2/3 of mouse auditory cortex

Parameter Pyramidal neurons SST interneurons PV interneurons
Average membrane potential (mV) -74.1 ± 0.9 (n = 21) -63.3 ± 1.6 (n = 20) -66.3 ± 1.8 (n = 11)
Resting membrane potential (mV) -78.0 ± 0.7 (n = 21) -65.7 ± 1.7 (n = 20) -72.2 ± 1.5 (n = 11)
Input resistance (MΩ) 51.1 ± 2.9 (n = 21) 97.9 ± 6.2 (n = 20) 43.9 ± 7.8 (n = 11)
AP half-width (ms) 1.65 ± 0.07 (n = 20) 1.02 ± 0.06 (n = 20) 0.56 ± 0.04 (n = 11)
AP threshold (mV) -40.9 ± 1.3 (n = 20) -41.4 ± 1.0 (n = 20) -46.4 ± 0.9 (n = 11)
Spontaneous spiking rate (Hz) 0.03 ± 0.01 (n = 19) 1.3 ± 0.3 (n = 14) 9.3 ± 3.1 (n = 11)
Maximum spiking rate* (Hz) 45.5 ± 5.2 (n = 18) 75.7 ± 9.0 (n = 19) 163.3 ± 20.0 (n = 11)
  • Data are given as mean ± SEM.

  • The dataset for analyzing electrophysiological properties is 21 Exc neurons, 20 SST neurons, and 11 PV neurons. The smaller sample size of some parameters for pyramidal neurons and SST interneurons is due to the lack of APs in few recordings.

  • *Maximum spiking rates are underestimates of the true maximum rates.


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 2-3 Auditory cortex layer 2/3 pyramidal excitatory neurons input resistance (MΩ) 51.1 ± 2.9 (21) 51.1 (MΩ) Data Table
Neocortex pyramidal cell layer 2-3 Auditory cortex layer 2/3 somatostatin-expressing GABAergic interneurons input resistance (MΩ) 97.9 ± 6.2 (20) 97.9 (MΩ) Data Table
Neocortex basket cell Auditory cortex layer 2/3 parvalbumin-expressing GABAergic interneurons input resistance (MΩ) 43.9 ± 7.8 (11) 43.9 (MΩ) Data Table
Neocortex pyramidal cell layer 2-3 Auditory cortex layer 2/3 pyramidal excitatory neurons spike half-width (ms) 1.65 ± 0.07 (20) 1.65 (ms) Data Table
Neocortex pyramidal cell layer 2-3 Auditory cortex layer 2/3 somatostatin-expressing GABAergic interneurons spike half-width (ms) 1.02 ± 0.06 (20) 1.02 (ms) Data Table
Neocortex basket cell Auditory cortex layer 2/3 parvalbumin-expressing GABAergic interneurons spike half-width (ms) 0.56 ± 0.04 (11) 0.56 (ms) Data Table
Neocortex pyramidal cell layer 2-3 Auditory cortex layer 2/3 pyramidal excitatory neurons spike threshold (mV) -40.9 ± 1.3 (20) -40.9 (mV) Data Table
Neocortex pyramidal cell layer 2-3 Auditory cortex layer 2/3 somatostatin-expressing GABAergic interneurons spike threshold (mV) -41.4 ± 1.0 (20) -41.4 (mV) Data Table
Neocortex basket cell Auditory cortex layer 2/3 parvalbumin-expressing GABAergic interneurons spike threshold (mV) -46.4 ± 0.9 (11) -46.4 (mV) Data Table
Neocortex pyramidal cell layer 2-3 Auditory cortex layer 2/3 pyramidal excitatory neurons spontaneous firing rate (Hz) 0.03 ± 0.01 (19) 0.03 (Hz) Data Table
Neocortex pyramidal cell layer 2-3 Auditory cortex layer 2/3 somatostatin-expressing GABAergic interneurons spontaneous firing rate (Hz) 1.3 ± 0.3 (14) 1.3 (Hz) Data Table
Neocortex basket cell Auditory cortex layer 2/3 parvalbumin-expressing GABAergic interneurons spontaneous firing rate (Hz) 9.3 ± 3.1 (11) 9.3 (Hz) Data Table
Neocortex pyramidal cell layer 2-3 Auditory cortex layer 2/3 pyramidal excitatory neurons maximum firing rate (Hz) 45.5 ± 5.2 (18) 45.5 (Hz) Data Table
Neocortex pyramidal cell layer 2-3 Auditory cortex layer 2/3 somatostatin-expressing GABAergic interneurons maximum firing rate (Hz) 75.7 ± 9.0 (19) 75.7 (Hz) Data Table
Neocortex basket cell Auditory cortex layer 2/3 parvalbumin-expressing GABAergic interneurons maximum firing rate (Hz) 163.3 ± 20.0 (11) 163.3 (Hz) Data Table
Neocortex pyramidal cell layer 2-3 Auditory cortex layer 2/3 pyramidal excitatory neurons resting membrane potential (mV) -78.0 ± 0.7 (21) -78.0 (mV) Data Table
Neocortex pyramidal cell layer 2-3 Auditory cortex layer 2/3 somatostatin-expressing GABAergic interneurons resting membrane potential (mV) -65.7 ± 1.7 (20) -65.7 (mV) Data Table
Neocortex basket cell Auditory cortex layer 2/3 parvalbumin-expressing GABAergic interneurons resting membrane potential (mV) -72.2 ± 1.5 (11) -72.2 (mV) Data Table