Article: Cellular mechanisms for response heterogeneity among L2/3 pyramidal cells in whisker somatosensory cortex.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Elstrott J; Clancy KB; Jafri H; Akimenko I; Feldman DE J. Neurophysiol., 2014
Properties | Low Threshold (35 cells) | High Threshold (34 cells) | P Value |
---|---|---|---|
Burst step, pA above rheobase | 274 ± 13 | 173 ± 16 | <0.0001 |
Burst step, absolute pA | 528 ± 13.7 | 436 ± 21 | <0.001 |
Spike threshold, mV | -35.5 ± 0.5 | -37.1 ± 0.4 | <0.01 |
Spike threshold - Vrest, mV | 39.1 ± 0.7 | 36.2 ± 0.6 | <0.01 |
Vrest, mV | -74.6 ± 0.5 | -73.3 ± 0.6 | 0.059 |
Rheobase, pA | 254 ± 11 | 273 ± 14 | n.s. |
Sag ratio (Ih) (26 and 30 cells), mV | 1.0 ± 0.1 | 1.3 ± 0.1 | n.s. |
Cm, pF | 279 ± 16.8 | 288 ± 27.7 | n.s. |
mAHP magnitude, mV | -5.4 ± 0.3 | -5.8 ± 0.3 | n.s. |
Rinput, MΩ | 77.8 ± 3.2 | 73.5 ± 2.8 | n.s. |
Age, days | 19 ± 0.3 | 20 ± 0.2 | n.s. |
Recording depth, μm | 68.1 ± 2.1 | 71.6 ± 2.6 | n.s. |
Distance below pia, μm | 320.9 ± 11.6 (34 cells) | 315.2 ± 13.2 (29 cells) | n.s. |
Values are means ± SE. Burst step, current injection required to evoke an initial spike doublet with <10-ms interspike interval; Vrest, resting potential; Cm, membrane capacitance; Rinput, input resistance; n.s., not significant.