AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Tuning of fast-spiking interneuron properties by an activity-dependent transcriptional switch.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Dehorter N; Ciceri G; Bartolini G; Lim L; del Pino I; Marín O
Science, 2015


Figure S2: Fig. S2. Electrophysiological properties of Er81+ and Er81 PV+ interneurons in cortical layer II-III.
Er81+ Er81- P values
Vrest (mV) -70.0 +/- 0.6 -67.5 +/- 1.6 0.09
Cm (pF) 31.9 +/- 2.8 31.2 +/- 3.8 0.88
Rm (MOhm) 135.3 +/- 6.8 124.1 +/- 7.3 0.3
Rheobase (pA) 273.0 +/- 20.4 186.5 +/- 42.2 (*) 0.04
V threshold (mV) -32.2 +/- 0.6 -37.3 +/- 2.6 (*) 0.02
AP amplitude (mV) 52.7 +/- 1.6 52.2 +/- 2.9 0.97
AP rise duration (ms) 0.22 +/- 0.01 0.27 +/- 0.02 (*) 0.02
AP tot duration (ms) 0.71 +/- 0.03 0.90 +/- 0.05 (**) 0.002
AHP amplitude (mV) 20.21 +/- 0.65 20.50 +/- 1.40 0.83
AHP duration (ms) 0.12 +/- 0.01 0.15 +/- 0.01 0.07
Latency to the 1st spike (ms) 297.0 +/- 16.8 147.6 +/- 24.5 (*) 0.03
MFF (Hz) 140.9 +/- 10.2 151.4 +/- 16.0 0.57
Number of cells 22 11
(A) Intrinsic electrophysiological properties of Er81+ and Er81- PV+ interneurons in cortical layer II-III at P25. Vrest: resting membrane potential; Cm: membrane capacitance; Rm: membrane resistance; Vthreshold: Threshold potential for spike; AP: Action potential; AHP: After hyperpolarization; MFF: Maximum firing frequency:

Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex interneuron deep Neocortex layer 2-3 fast spiking Transcription factor Er81 expressing parvalbumin-expressing internuron input resistance 135.3 ± 6.8 (22) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking non-transcription factor Er81 expressing parvalbumin-expressing internuron input resistance 124.1 ± 7.3 (11) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking Transcription factor Er81 expressing parvalbumin-expressing internuron rheobase (pA) 273.0 ± 20.4 (22) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking non-transcription factor Er81 expressing parvalbumin-expressing internuron rheobase (pA) 186.5 ± 42.2 (11) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking Transcription factor Er81 expressing parvalbumin-expressing internuron spike threshold (mV) -32.2 ± 0.6 (22) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking non-transcription factor Er81 expressing parvalbumin-expressing internuron spike threshold (mV) -37.3 ± 2.6 (11) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking Transcription factor Er81 expressing parvalbumin-expressing internuron resting membrane potential (mV) -70.0 ± 0.6 (22) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking Transcription factor Er81 expressing parvalbumin-expressing internuron spike amplitude (mV) 52.7 ± 1.6 (22) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking non-transcription factor Er81 expressing parvalbumin-expressing internuron spike amplitude (mV) 52.2 ± 2.9 (11) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking Transcription factor Er81 expressing parvalbumin-expressing internuron spike rise time (ms) 0.22 ± 0.01 (22) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking non-transcription factor Er81 expressing parvalbumin-expressing internuron spike rise time (ms) 0.27 ± 0.02 (11) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking non-transcription factor Er81 expressing parvalbumin-expressing internuron resting membrane potential (mV) -67.5 ± 1.6 (11) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking Transcription factor Er81 expressing parvalbumin-expressing internuron spike width (ms) 0.71 ± 0.03 (22) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking non-transcription factor Er81 expressing parvalbumin-expressing internuron spike width (ms) 0.9 ± 0.05 (11) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking Transcription factor Er81 expressing parvalbumin-expressing internuron AHP amplitude (mV) 20.21 ± 0.65 (22) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking non-transcription factor Er81 expressing parvalbumin-expressing internuron AHP amplitude (mV) 20.5 ± 1.4 (11) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking Transcription factor Er81 expressing parvalbumin-expressing internuron AHP duration (ms) 0.12 ± 0.01 (22) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking non-transcription factor Er81 expressing parvalbumin-expressing internuron AHP duration (ms) 0.15 ± 0.01 (11) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking Transcription factor Er81 expressing parvalbumin-expressing internuron first spike latency (ms) 297.0 ± 16.8 (22) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking non-transcription factor Er81 expressing parvalbumin-expressing internuron first spike latency (ms) 147.6 ± 24.5 (11) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking Transcription factor Er81 expressing parvalbumin-expressing internuron maximum firing rate (Hz) 140.9 ± 10.2 (22) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking non-transcription factor Er81 expressing parvalbumin-expressing internuron maximum firing rate (Hz) 151.4 ± 16.0 (11) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking Transcription factor Er81 expressing parvalbumin-expressing internuron cell capacitance (pF) 31.9 ± 2.8 (22) -- Data Table
Neocortex interneuron deep Neocortex layer 2-3 fast spiking non-transcription factor Er81 expressing parvalbumin-expressing internuron cell capacitance (pF) 31.2 ± 3.8 (11) -- Data Table