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Article: Dietary prenatal choline supplementation alters postnatal hippocampal structure and function.

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Li Q; Guo-Ross S; Lewis DV; Turner D; White AM; Wilson WA; Swartzwelder HS
J. Neurophysiol., 2004



TABLE 2.Passive membrane properties of CA1 pyramidal cells recorded from control and choline supplemented rats
Parameters
Control
n
 Supplementation
n
 P value
Resting membrane potential (mV) -66 ± 4.97 50 -65 ± 6.08 53 0.264
Input resistance (MΩ) 82.8 ± 5.44 34 70.3 ± 2.73 37 0.044
Membrane time constant (ms) 20.52 ± 1.02 33 20.56 ± 0.93 31 0.981
Sag ratio 0.79 ± 0.09 25 0.80 ± 0.11 33 0.903
Input resistance (MΩ) in 5 mM CsCl 157.1 ± 14.1 11 142.7 ± 10.2 11 0.418
Membrane time constant (ms) in 5 mM CsCL
54.4 ± 2.06
13
50.3 ± 1.73
12
0.447
Values are mean ± SE.

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -66.0 ± 4.97 (50) -66.0 (mV) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 82.8 ± 5.44 (34) 82.8 (MΩ) Data Table
Hippocampus CA1 pyramidal cell membrane time constant (ms) 20.52 ± 1.02 (33) 20.52 (ms) Data Table
Hippocampus CA1 pyramidal cell sag ratio 0.79 ± 0.09 (25) 0.79 (ratio) Data Table