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Article: Dietary prenatal choline supplementation alters postnatal hippocampal structure and function.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Li Q; Guo-Ross S; Lewis DV; Turner D; White AM; Wilson WA; Swartzwelder HS
J. Neurophysiol., 2004



TABLE 3.Action potential properties of CA1 pyramidal cells recorded from control and choline supplemented rats


Parameters

Control

n

Supplementation

n

P value

Spike threshold (mV) -43.5 ± 0.74 32 44.6 ± 0.75 32 0.145
Rheobase (pA) 76.2 ± 4.9 32 66.6 ± 4.2 32 0.069
Spike amplitude (mV)
 x=ns\x=ns First spike 97.1 ± 1.8 32 94.2 ± 2.0 32 0.151
 x=ns\x=ns Second spike 93.6 ± 1.5 32 89.7 ± 1.8 32 0.061
 x=ns\x=ns Third spike 93.4 ± 1.2 32 90.1 ± 1.8 32 0.063
Spike duration (ms)
 x=ns\x=ns First spike 3.22 ± 0.15 32 3.12 ± 0.09 32 0.288
 x=ns\x=ns Second spike 3.39 ± 0.12 32 3.29 ± 0.12 32 0.269
 x=ns\x=ns Third spike 3.57 ± 0.09 32 3.50 ± 0.10 32 0.306
Spike duration at half amplitude (ms)
 x=ns\x=ns First spike 1.25 ± 0.06 32 1.22 ± 0.06 32 0.364
 x=ns\x=ns Second spike 1.58 ± 0.09 32 1.52 ± 0.08 32 0.303
 x=ns\x=ns Third spike 1.57 ± 0.08 32 1.50 ± 0.08 32 0.239
ADP (mV) 1.19 ± 0.08 24 3.84 ± 0.34 24 0.0008
ADP duration (ms)

4.37 ± 0.78

24

7.12 ± 0.82

24

0.008


Values are mean ± SE. ADP, afterdepolarizing potential.

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell spike threshold (mV) -43.5 ± 0.74 (32) -43.5 (mV) Data Table
Hippocampus CA1 pyramidal cell ADP duration (ms) 4.37 ± 0.78 (32) 4.37 (ms) Data Table
Hippocampus CA1 pyramidal cell rheobase (pA) 76.2 ± 4.9 (32) 76.2 (pA) Data Table
Hippocampus CA1 pyramidal cell spike amplitude 97.1 ± 1.8 (32) 97.1 (mV) Data Table
Hippocampus CA1 pyramidal cell spike width 3.22 ± 0.15 (32) 3.22 (ms) Data Table
Hippocampus CA1 pyramidal cell spike half-width 1.25 ± 0.06 (32) 1.25 (ms) Data Table
Hippocampus CA1 pyramidal cell ADP amplitude (mV) 1.19 ± 0.08 (32) 1.19 (mV) Data Table