*Calculated from the voltage deflection in response to a −100 pA current injection. †Measured from first spike in response to a +300 pA depolarizing current injection. ‡ADP measured following a single action potential elicited by a 2 ms, +2 nA depolarizing current injection. | |
Resting membrane potential | −75 ± 1 mV |
Membrane time constant (*) | 48.4 ± 1.3 ms |
Input resistance (*) | 167 ± 4 MΩ |
Extrapolated input resistance (*) | 204 ± 5 MΩ |
% sag (*) | 17.3 ± 1.1% |
Mean number of action potentials (current injection: 300/200 pA) | 10.4 ± 0.5/8.0 ± 0.5 |
Action potential threshold† | −58.1 ± 0.3 mV |
Action potential peak† | 29.0 ± 0.5 mV |
Action potential width at 0 mV† | 0.57 ± 0.01 ms |
ADP amplitude‡ | 15.2 ± 0.5 mV |
n | 95 |
Article: Activity-dependent depression of the spike after-depolarization generates long-lasting intrinsic plasticity in hippocampal CA3 pyramidal neurons.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Brown JT; Randall AD J. Physiol. (Lond.), 2009