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Article: Similar electrophysiological changes in axotomized and neighboring intact dorsal root ganglion neurons.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Ma C; Shu Y; Zheng Z; Chen Y; Yao H; Greenquist KW; White FA; LaMotte RH
J. Neurophysiol., 2003


Table 2.

Electrophysiological properties of DRG neurons with axotomized or intact central axons after PR

Size Category Large Medium Small
Treatment Sham Uncut Cut Sham Cut Cut Sham Uncut Cut
Cell size, um 51.7  ±  1.0 49.6  ±  0.7 51.3  ±  1.3 39.6  ±  0.8 39.1  ±  0.7 38.9  ±  1.0 27.2  ±  0.6 25.0  ±  1.2 28.5  ±  1.4
 n 18 17 17 24 17 17 13 14 4
RMP, mV −56.4  ±  2.0 −57.2  ±  2.0 −58.6  ±  1.6 −55.6  ±  1.7 −55.5  ±  2.0 −56.1  ±  1.6 −50.9  ±  2.5 −52.6  ±  2.5 −52.9  ±  4.4
 n 18 17 17 24 17 17 13 14 4
Rin, Mohm 9.0  ±  1.5 13.1  ±  2.0 20.2  ±  4.0 15.8  ±  2.0 18.1  ±  3.1 28.4  ±  3.7 50.9  ±  8.3 30.4  ±  3.8 22.3  ±  5.2
 n 16 17 16* 24 16 162-160 † 13 14 3
Curr. thre., nA 1.85  ±  0.33 2.18  ±  0.34 1.70  ±  0.38 1.76  ±  0.27 1.63  ±  0.32 2.08  ±  0.44 0.84  ±  0.17 1.83  ±  0.49 0.70  ±  0.15
 n 16 16 12 23 14 13 13 11 3
Vol. thre., mV −44.8  ±  4.6 −54.9  ±  2.1 −56.2  ±  2.0 −36.4  ±  3.9 −54.5  ±  2.3 −48.3  ±  2.9 −29.5  ±  3.8 −28.7  ±  6.0 −31.0  ±  11.6
 n 10 12* 10* 20 92-160 14* 13 10 2
APD50, ms 0.60  ±  0.04 0.62  ±  0.06 0.66  ±  0.11 0.93  ±  0.09 0.79  ±  0.09 0.83  ±  0.09 1.68  ±  0.17 1.84  ±  0.25 2.22  ±  0.70
 n 6 12 10 18 10 15 12 12 3
dV/dt r., mV/ms 198  ±  20.6 225  ±  19.9 229  ±  30.7 170  ±  15.8 183  ±  21.0 201  ±  20.1 155  ±  16.5 133  ±  17.4 85.6  ±  36.3
 n 7 12 10 18 10 15 12 12 3
dV/dt f., mV/ms −133  ±  11.9 −131  ±  9.1 −144  ±  22.3 −100  ±  11.0 −124  ±  14.0 −123  ±  8.4 −69.8  ±  7.8 −60.1  ±  9.9 −48.8  ±  16.4
 n 7 12 10 18 10 15 12 12 3
AHP50, ms 3.35  ±  1.18 4.71  ±  0.79 4.81  ±  1.44 6.05  ±  1.44 8.15  ±  2.18 4.69  ±  1.15 6.19  ±  0.80 5.28  ±  1.13 6.02  ±  2.44
 n 7 12 10 21 10 15 12 10 3
AHP amp., mV −13.1  ±  2.3 −11.1  ±  0.8 −10.2  ±  1.1 −13.5  ±  0.9 −10.0  ±  1.6 −11.5  ±  0.8 −15.0  ±  1.6 −12.3  ±  1.9 −11.6  ±  3.7
 n 7 12 10 21 9 15 12 10 3

  • PR: L5 dorsal root partial rhizotomy; uncut: neurons with intact dorsal root fibers, cut: neurons with cut dorsal root fibers in PR rats, Sham: DRG neurons from Sham-operative rats; Cell size: mean diameter of neuron;

  • ↵*  P < 0.05,

  • ↵F2-160  P < 0.01, cut or uncut vs. Sham;

  • ↵†  P < 0.05, cut vs. uncut. Other parameters are same as Table 1.


Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Dorsal root ganglion cell cell diameter (um) 51.7 ± 1.0 (18) 51.7 (um) Data Table
Dorsal root ganglion cell cell diameter (um) 39.6 ± 0.8 (24) 39.6 (um) Data Table
Dorsal root ganglion cell cell diameter (um) 27.2 ± 0.6 (13) 27.2 (um) Data Table
Dorsal root ganglion cell resting membrane potential (mV) -56.4 ± 2.0 (18) -56.4 (mV) Data Table
Dorsal root ganglion cell resting membrane potential (mV) -55.6 ± 1.7 (24) -55.6 (mV) Data Table
Dorsal root ganglion cell resting membrane potential (mV) -50.9 ± 2.5 (13) -50.9 (mV) Data Table
Dorsal root ganglion cell input resistance (Mohm) 9.0 ± 1.5 (18) 9.0 (MΩ) Data Table
Dorsal root ganglion cell input resistance (Mohm) 15.8 ± 2.0 (24) 15.8 (MΩ) Data Table
Dorsal root ganglion cell input resistance (Mohm) 50.9 ± 8.3 (13) 50.9 (MΩ) Data Table
Dorsal root ganglion cell rheobase (nA) 1.85 ± 0.33 (18) 1850.0 (pA) Data Table
Dorsal root ganglion cell rheobase (nA) 1.76 ± 0.27 (24) 1760.0 (pA) Data Table
Dorsal root ganglion cell rheobase (nA) 0.84 ± 0.17 (13) 840.0 (pA) Data Table
Dorsal root ganglion cell spike threshold (mV) -44.8 ± 4.6 (18) -44.8 (mV) Data Table
Dorsal root ganglion cell spike threshold (mV) -36.4 ± 3.9 (24) -36.4 (mV) Data Table
Dorsal root ganglion cell spike threshold (mV) -29.5 ± 3.8 (13) -29.5 (mV) Data Table
Dorsal root ganglion cell ADP duration (ms) 0.6 ± 0.04 (18) 0.6 (ms) Data Table
Dorsal root ganglion cell ADP duration (ms) 0.93 ± 0.09 (24) 0.93 (ms) Data Table
Dorsal root ganglion cell ADP duration (ms) 1.68 ± 0.17 (13) 1.68 (ms) Data Table
Dorsal root ganglion cell spike max rise slope (mV/ms) 198.0 ± 20.6 (18) 198.0 (mV/ms) Data Table
Dorsal root ganglion cell spike max rise slope (mV/ms) 170.0 ± 15.8 (24) 170.0 (mV/ms) Data Table
Dorsal root ganglion cell spike max rise slope (mV/ms) 155.0 ± 16.5 (13) 155.0 (mV/ms) Data Table
Dorsal root ganglion cell spike max decay slope (mV/ms) -133.0 ± 11.9 (18) 133.0 (mV/ms) Data Table
Dorsal root ganglion cell spike max decay slope (mV/ms) -100.0 ± 11.0 (24) 100.0 (mV/ms) Data Table
Dorsal root ganglion cell spike max decay slope (mV/ms) -69.8 ± 7.8 (13) 69.8 (mV/ms) Data Table
Dorsal root ganglion cell AHP amplitude (mV) -13.1 ± 2.3 (18) 13.1 (mV) Data Table
Dorsal root ganglion cell AHP amplitude (mV) -13.5 ± 0.9 (24) 13.5 (mV) Data Table
Dorsal root ganglion cell AHP amplitude (mV) -15.0 ± 1.6 (13) 15.0 (mV) Data Table