Wild-Type | Kv3.1−/− | |
---|---|---|
Membrane potential, mV | −75.9 ± 1.7 | −73.5 ± 2.3 |
Input resistance, MΩ | 273.8 ± 26.8 | 273.5 ± 26.2 |
23°C | ||
AP amplitude, mV | 80.8 ± 1.8 | 75.7 ± 1.5* |
AP max rate of depolarization, V/s | 350.6 ± 14.6 | 330.1 ± 10.6 |
AP max rate of repolarization, V/s | −241.4 ± 13.3 | −229.1 ± 7.8 |
AP half-width, ms | 0.46 ± 0.02 | 0.43 ± 0.01 |
AP fAHP, mV | −20.2 ± 1.2 | −16.9 ± 0.9* |
AP threshold, mV | −50.9 ± 3.6 | −50.1 ± 3.7 |
34°C | ||
AP amplitude, mV | 67.4 ± 1.5 | 61.1 ± 3.0 |
AP max rate of depolarization, V/s | 515.4 ± 25.8 | 449.5 ± 26.1 |
AP max rate of repolarization, V/s | −543.5 ± 49.6 | −381.7 ± 18.21-160 |
AP half-width, ms | 0.19 ± 0.01 | 0.23 ± 0.011-165 |
AP fAHP, mV | −22.3 ± 1.3 | −20.3 ± 1.4 |
AP threshold, mV | −47.5 ± 1.1 | −47.1 ± 1.7 |
Article: Resilient RTN fast spiking in Kv3.1 null mice suggests redundancy in the action potential repolarization mechanism.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Porcello DM; Ho CS; Joho RH; Huguenard JR J. Neurophysiol., 2002