AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Cerebellum Purkinje cell (Definition)

Electrophysiological properties of Cerebellum Purkinje cells from literature:

  • Reports: Blue dots indicate human-curated values; Orange dots indicate non-human curated values
  • Mean+SD: mean and standard deviation of human-curated neuron measurements
  • All neurons: mean and standard deviation computed over all neurons in database
  • Interactivity:
  • Mouse over neuron report data points and click to view corresponding publication
  • Mouse over y- axis labels to view definition or click to view values across neuron types
  • Zoom in on a section of plot by dragging cursor. Zoom out by double clicking on plot.
  • Legend: Blue dots = text-mined values human curated; Orange dots = text-mined values not human curated

View data in table form

Articles with extracted electrophysiology properties:

Article Title Authors Journal Year Electrophys values Neuron types
The leaner P/Q-type calcium channel mutation renders cerebellar Purkinje neurons hyper-excitable and eliminates Ca2+-Na+ spike bursts. (NeuroElectro data) (PubMed) Ovsepian SV; Friel DD Eur. J. Neurosci. 2008 5 1
Aminopyridines correct early dysfunction and delay neurodegeneration in a mouse model of spinocerebellar ataxia type 1. (NeuroElectro data) (PubMed) Hourez R; Servais L; Orduz D; Gall D; Millard I; de Kerchove d'Exaerde A; Cheron G; Orr HT; Pandolfo M; Schiffmann SN J. Neurosci. 2011 9 1
Purkinje-cell-restricted restoration of Kv3.3 function restores complex spikes and rescues motor coordination in Kcnc3 mutants. (NeuroElectro data) (PubMed) Hurlock EC; McMahon A; Joho RH J. Neurosci. 2008 4 1
Robustness of burst firing in dissociated purkinje neurons with acute or long-term reductions in sodium conductance. (NeuroElectro data) (PubMed) Swensen AM; Bean BP J. Neurosci. 2005 4 1
Calcium dynamics and electrophysiological properties of cerebellar Purkinje cells in SCA1 transgenic mice. (NeuroElectro data) (PubMed) Inoue T; Lin X; Kohlmeier KA; Orr HT; Zoghbi HY; Ross WN J. Neurophysiol. 2001 5 1
Presynaptic origin of paired-pulse depression at climbing fibre-Purkinje cell synapses in the rat cerebellum. (NeuroElectro data) (PubMed) Hashimoto K; Kano M J. Physiol. (Lond.) 1998 4 1
Lobule-specific membrane excitability of cerebellar Purkinje cells. (NeuroElectro data) (PubMed) Kim CH; Oh SH; Lee JH; Chang SO; Kim J; Kim SJ J. Physiol. (Lond.) 2012 48 1
Submillisecond optical reporting of membrane potential in situ using a neuronal tracer dye. (NeuroElectro data) (PubMed) Bradley J; Luo R; Otis TS; DiGregorio DA J. Neurosci. 2009 4 1
Impaired synaptic plasticity and cAMP response element-binding protein activation in Ca2+/calmodulin-dependent protein kinase type IV/Gr-deficient mice. (NeuroElectro data) (PubMed) Ho N; Liauw JA; Blaeser F; Wei F; Hanissian S; Muglia LM; Wozniak DF; Nardi A; Arvin KL; Holtzman DM; Linden DJ; Zhuo M; Muglia LJ; Chatila TA J. Neurosci. 2000 1 1
Activation of presynaptic cAMP-dependent protein kinase is required for induction of cerebellar long-term potentiation. (NeuroElectro data) (PubMed) Linden DJ; Ahn S J. Neurosci. 1999 1 1
Physiological and morphological development of the rat cerebellar Purkinje cell. (NeuroElectro data) (PubMed) McKay BE; Turner RW J. Physiol. (Lond.) 2005 120 1
Selective and regulated gene expression in murine Purkinje cells by in utero electroporation. (NeuroElectro data) (PubMed) Nishiyama J; Hayashi Y; Nomura T; Miura E; Kakegawa W; Yuzaki M Eur. J. Neurosci. 2012 2 1
In vivo transduction of murine cerebellar Purkinje cells by HIV-derived lentiviral vectors. (NeuroElectro data) (PubMed) Torashima T; Okoyama S; Nishizaki T; Hirai H Brain Res. 2006 3 1
Impaired cerebellar long-term potentiation in type I adenylyl cyclase mutant mice. (NeuroElectro data) (PubMed) Storm DR; Hansel C; Hacker B; Parent A; Linden DJ Neuron 1998 4 2
Chronic ethanol treatment alters AMPA-induced calcium signals in developing Purkinje neurons. (NeuroElectro data) (PubMed) Netzeband JG; Trotter C; Parsons KL; Gruol DL Brain Res. 1999 2 1
Membrane excitability and fear conditioning in cerebellar Purkinje cell. (NeuroElectro data) (PubMed) Zhu L; Scelfo B; Tempia F; Sacchetti B; Strata P Neuroscience 2006 6 1
Excitability and synaptic alterations in the cerebellum of APP/PS1 mice. (NeuroElectro data) (PubMed) Hoxha E; Boda E; Montarolo F; Parolisi R; Tempia F PLoS ONE 2012 14 1
Enhancement of both long-term depression induction and optokinetic response adaptation in mice lacking delphilin. (NeuroElectro data) (PubMed) Takeuchi T; Ohtsuki G; Yoshida T; Fukaya M; Wainai T; Yamashita M; Yamazaki Y; Mori H; Sakimura K; Kawamoto S; Watanabe M; Hirano T; Mishina M PLoS ONE 2008 6 1
Maternal mobile phone exposure adversely affects the electrophysiological properties of Purkinje neurons in rat offspring. (NeuroElectro data) (PubMed) Haghani M; Shabani M; Moazzami K Neuroscience 2013 14 1

Expert curators for Cerebellum Purkinje cells:

No assigned expert curators:

Become a neuron curator (login required)

More information about Cerebellum Purkinje cells in other resources: