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Article: Ghrelin stimulation of growth hormone-releasing hormone neurons is direct in the arcuate nucleus.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Osterstock G; Escobar P; Mitutsova V; Gouty-Colomer LA; Fontanaud P; Molino F; Fehrentz JA; Carmignac D; Martinez J; Guerineau NC; Robinson IC; Mollard P; Méry PF
PLoS ONE, 2010

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Paraventricular hypothalamic nucleus neurons arcuate hypothalamic nucleus growth hormone-releasing hormone neuron AHP amplitude -7.7 ± 1.1 (8) 7.7 (mV) Data Table
Paraventricular hypothalamic nucleus neurons arcuate hypothalamic nucleus growth hormone-releasing hormone neuron AHP voltage -54.0 ± 3.8 (8) -54.0 (mV) Data Table
Paraventricular hypothalamic nucleus neurons arcuate hypothalamic nucleus growth hormone-releasing hormone neuron spike amplitude 49.8 ± 3.5 (8) 49.8 (mV) Data Table
Paraventricular hypothalamic nucleus neurons arcuate hypothalamic nucleus growth hormone-releasing hormone neuron spike decay time 12.2 ± 0.94 (8) -- Data Table
Paraventricular hypothalamic nucleus neurons arcuate hypothalamic nucleus growth hormone-releasing hormone neuron spike half-width 1.6 ± 0.13 (8) 1.6 (ms) Data Table
Paraventricular hypothalamic nucleus neurons arcuate hypothalamic nucleus growth hormone-releasing hormone neuron spike peak 4.6 ± 3.0 (8) 4.6 (mV) Data Table
Paraventricular hypothalamic nucleus neurons arcuate hypothalamic nucleus growth hormone-releasing hormone neuron spike rise time 5.92 ± 0.46 (8) 5.92 (ms) Data Table
Paraventricular hypothalamic nucleus neurons arcuate hypothalamic nucleus growth hormone-releasing hormone neuron spike threshold -45.7 ± 3.4 (8) -45.7 (mV) Data Table

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Metadata values

Experimental condition Value
Species Mice
Strain Mice, Transgenic
PrepType in vitro
ExternalSolution 5.0
external_1_pH 7.4
external_1_Mg 1.0
external_1_Ca 2.0
external_1_Na 142.25
external_1_Cl 146.5
external_1_K 2.5
InternalSolution 5.0
internal_1_pH 7.2
internal_1_Mg 3.0
internal_1_Na 12.5
internal_1_Cl 4.25
internal_1_K 127.55
ElectrodeType Perforated patch
JxnPotential Unreported
AnimalAge 84.0 - 112.0
RecTemp 30.0 - 32.0
internal_0_pH 7.2
internal_0_Mg 3.0
internal_0_Na 12.5
internal_0_K 127.55
internal_0_GTP 0.5
internal_0_ATP 2.0
internal_0_EGTA 0.1
internal_0_HEPES 10.0
internal_0_Cl 4.25
external_0_pH 7.4
external_0_Mg 1.0
external_0_Na 152.25
external_0_K 2.5
external_0_Cl 133.5
external_0_Ca 2.0
external_0_glucose 12.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
32858 Ghrelin stimulation of growth hormone-releasing hormone neurons is direct in the arcuate nucleus. Osterstock G; Escobar P; Mitutsova V; Gouty-Colomer LA; Fontanaud P; Molino F; Fehrentz JA; Carmignac D; Martinez J; Guerineau NC; Robinson IC; Mollard P; Méry PF PLoS ONE 2010 False 8 Shreejoy Tripathy, Kerrie Tsigounis, 1