NeuroElectro Publications

Article: Reduced seizure threshold and altered network oscillatory properties in a mouse model of Rett syndrome.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
McLeod F; Ganley R; Williams L; Selfridge J; Bird A; Cobb SR
Neuroscience, 2013

Inferred neuron-electrophysiology data values

Neuron Type	Neuron Description	Ephys Prop	Extracted Value	Standardized Value	Content Source
Hippocampus CA1 pyramidal cell		input resistance (MΩ)	125.8 ± 11.0 (14)	125.8 (MΩ)	Data Table
Hippocampus CA1 pyramidal cell		medium AHP amplitude (mV)	11.1 ± 4.3 (14)	11.1 (mV)	Data Table
Hippocampus CA1 pyramidal cell		membrane time constant (ms)	31.4 ± 2.6 (14)	31.4 (ms)	Data Table
Hippocampus CA1 pyramidal cell		resting membrane potential (mV)	-61.7 ± 1.6 (14)	-61.7 (mV)	Data Table
Hippocampus CA1 pyramidal cell		spike amplitude (mV)	84.2 ± 2.8 (14)	84.2 (mV)	Data Table
Hippocampus CA1 pyramidal cell		spike half-width (ms)	1.04 ± 0.06 (14)	1.04 (ms)	Data Table
Hippocampus CA1 pyramidal cell		spike max decay slope	106.0 ± 7.0 (14)	106.0 (mV/ms)	Data Table
Hippocampus CA1 pyramidal cell		spike max rise slope	582.0 ± 41.0 (14)	582.0 (mV/ms)	Data Table
Hippocampus CA1 pyramidal cell		spike rise time (ms)	0.08 ± 0.01 (14)	0.08 (ms)	Data Table
Hippocampus CA1 pyramidal cell		spike threshold (mV)	-37.7 ± 0.7 (14)	-37.7 (mV)	Data Table

Metadata values

Experimental condition	Value
Species	Mice
ElectrodeType	Patch-clamp
AnimalAge	35.0 - 125.0
ExternalSolution	5.0
external_1_Mg	1.0
external_1_Ca	2.0
external_1_Na	151.25
external_1_Cl	133.5
external_1_K	2.5
InternalSolution	5.0
PrepType	in vitro
JxnPotential	Unreported
RecTemp	34.0
Strain	C57BL
internal_0_Mg	2.0
internal_0_Na	6.6
internal_0_K	140.0
internal_0_GTP	0.3
internal_0_ATP	2.0
internal_0_EGTA	10.0
internal_0_HEPES	10.0
internal_0_Cl	14.0
external_0_Na	151.41
external_0_K	3.0
external_0_Cl	131.0
external_0_Ca	2.0
external_0_glucose	9.09

Data table listing

Data Table	Article Title	Authors	Journal	Year	Table needs expert?	Ephys table mentions	Curated by	Times validated
47754	Reduced seizure threshold and altered network oscillatory properties in a mouse model of Rett syndrome.	McLeod F; Ganley R; Williams L; Selfridge J; Bird A; Cobb SR	Neuroscience	2013	False	10	Shreejoy Tripathy, Nathalie Binnion,	1