Article: Hippocampal heterotopia with molecular and electrophysiological properties of neocortical neurons.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Castro PA; Pleasure SJ; Baraban SC Neuroscience, 2002
Table 1Intrinsic neuronal properties
All data was analyzed using a Kruskal–Wallis one-way ANOVA with a post hoc Dunn’s test for multiple paired comparisons. *P<0.05 for comparisons between control cortex and control CA1; **P<0.05 for comparisons between control CA1 and MAM heterotopic. ***P<0.05 for comparisons between MAM heterotopic and MAM normotopic; ****P<0.05 for comparisons between control CA1 and control cortex. Each group represents data from between 4 and 13 neurons. Values represent mean ±S.E.M. RMP, resting membrane potential.
Cell type | RMP (mV) | Rin (MΩ) | AP rise (ms) | AP decay (ms) | AP half-width (ms) | AP amp. (mV) | AP thresh. (mV) | Sag amp. (mV) | Sag ratio | Spike AHP amp. (mV) | fAHP | fADP |
Control CA1 pyramidal | −66.6±0.6 | 142.1±7.9 | 0.24±0.01 | 0.41±0.02 | 0.66±0.03 | 97.4±3.2 | −47.9±1.09 | 4.9±0.4 | 1.38±0.02 | 73.7±3.5 | yes | yes |
Control cortex | −68.8±2.1 | 384.8±71.4*, **** | 0.24±0.04 | 0.42±0.12 | 0.65±0.13 | 87.2±8.5 | −39.5±3.2*, **** | 1.4±0.5*, **** | 1.06±0.03, **** | 279.4±48.3*, **** | no | no |
MAM heterotopic | −67.6±1.2 | 346.5±61.3**, *** | 0.35±0.04 | 0.88±0.13**, *** | 1.08±0.13**, *** | 92.2±2.7 | −36.4±1.0** | 1.5±0.3**, *** | 1.07±0.02**, *** | 341.5±69.9**, *** | no | no |
MAM normotopic | −67.2±1.4 | 153.5±15.1 | 0.23±0.02 | 0.43±0.03 | 0.66±0.04 | 103.6±3.9 | −43.1±3.8 | 5.3±1.0 | 1.39±0.04 | 67.9±8.2 | yes | yes |