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Dentate gyrus granule cell (Definition)

Electrophysiological properties of Dentate gyrus granule cells from literature:

  • Reports: Blue dots indicate human-curated values; Orange dots indicate non-human curated values
  • Mean+SD: mean and standard deviation of human-curated neuron measurements
  • All neurons: mean and standard deviation computed over all neurons in database
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  • Legend: Blue dots = text-mined values human curated; Orange dots = text-mined values not human curated

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Articles with extracted electrophysiology properties:

Article Title Authors Journal Year Electrophys values Neuron types
Specialized electrophysiological properties of anatomically identified neurons in the hilar region of the rat fascia dentata. (NeuroElectro data) (PubMed) Lübke J; Frotscher M; Spruston N J. Neurophysiol. 1998 32 4
Reduced inhibition of dentate granule cells in a model of temporal lobe epilepsy. (NeuroElectro data) (PubMed) Kobayashi M; Buckmaster PS J. Neurosci. 2003 2 1
Firing pattern of rat hippocampal neurons: a perforated patch clamp study. (NeuroElectro data) (PubMed) Podlogar M; Dietrich D Brain Res. 2006 10 2
A selective interplay between aberrant EPSPKA and INaP reduces spike timing precision in dentate granule cells of epileptic rats. (NeuroElectro data) (PubMed) Epsztein J; Sola E; Represa A; Ben-Ari Y; Crépel V Cereb. Cortex 2010 6 1
Calbindin-D28k content and firing pattern of hippocampal granule cells in amygdala-kindled rats: a perforated patch-clamp study. (NeuroElectro data) (PubMed) Dietrich D; Podlogar M; Ortmanns G; Clusmann H; Kral T Brain Res. 2005 9 1
Enhanced tonic GABA current in normotopic and hilar ectopic dentate granule cells after pilocarpine-induced status epilepticus. (NeuroElectro data) (PubMed) Zhan RZ; Nadler JV J. Neurophysiol. 2009 6 1
Aging alters dendritic morphology, input resistance, and inhibitory signaling in dentate granule cells of the rhesus monkey. (NeuroElectro data) (PubMed) Luebke JI; Rosene DL J. Comp. Neurol. 2003 14 1
Electrophysiological evidence of monosynaptic excitatory transmission between granule cells after seizure-induced mossy fiber sprouting. (NeuroElectro data) (PubMed) Scharfman HE; Sollas AL; Berger RE; Goodman JH J. Neurophysiol. 2003 12 1
GABA uptake and heterotransport are impaired in the dentate gyrus of epileptic rats and humans with temporal lobe sclerosis. (NeuroElectro data) (PubMed) Patrylo PR; Spencer DD; Williamson A J. Neurophysiol. 2001 4 1
Effect of adrenalectomy on membrane properties and synaptic potentials in rat dentate granule cells. (NeuroElectro data) (PubMed) Joëls M; Stienstra C; Karten Y J. Neurophysiol. 2001 6 1
In vivo intracellular analysis of granule cell axon reorganization in epileptic rats. (NeuroElectro data) (PubMed) Buckmaster PS; Dudek FE J. Neurophysiol. 1999 4 1
Transient neurophysiological changes in CA3 neurons and dentate granule cells after severe forebrain ischemia in vivo. (NeuroElectro data) (PubMed) Gao TM; Howard EM; Xu ZC J. Neurophysiol. 1998 12 2
Effects of prenatal cocaine exposure on the developing hippocampus: intrinsic and synaptic physiology. (NeuroElectro data) (PubMed) Baraban SC; Schwartzkroin PA J. Neurophysiol. 1997 70 3
Increased excitatory synaptic input to granule cells from hilar and CA3 regions in a rat model of temporal lobe epilepsy. (NeuroElectro data) (PubMed) Zhang W; Huguenard JR; Buckmaster PS J. Neurosci. 2012 5 1
Physiological and morphological characterization of dentate granule cells in the p35 knock-out mouse hippocampus: evidence for an epileptic circuit. (NeuroElectro data) (PubMed) Patel LS; Wenzel HJ; Schwartzkroin PA J. Neurosci. 2004 6 1
Granule-like neurons at the hilar/CA3 border after status epilepticus and their synchrony with area CA3 pyramidal cells: functional implications of seizure-induced neurogenesis. (NeuroElectro data) (PubMed) Scharfman HE; Goodman JH; Sollas AL J. Neurosci. 2000 20 1
Testing the disinhibition hypothesis of epileptogenesis in vivo and during spontaneous seizures. (NeuroElectro data) (PubMed) Buckmaster PS; Jongen-Rêlo AL; Davari SB; Wong EH J. Neurosci. 2000 3 1
Rapid reversal of impaired inhibitory and excitatory transmission but not spine dysgenesis in a mouse model of mental retardation. (NeuroElectro data) (PubMed) Powell AD; Gill KK; Saintot PP; Jiruska P; Chelly J; Billuart P; Jefferys JG J. Physiol. (Lond.) 2012 8 1
Interneurons of the dentate-hilus border of the rat dentate gyrus: morphological and electrophysiological heterogeneity. (NeuroElectro data) (PubMed) Mott DD; Turner DA; Okazaki MM; Lewis DV J. Neurosci. 1997 44 2
Functional properties of ES cell-derived neurons engrafted into the hippocampus of adult normal and chronically epileptic rats. (NeuroElectro data) (PubMed) Rüschenschmidt C; Koch PG; Brüstle O; Beck H Epilepsia 2005 5 1
Dentate filter function is altered in a proepileptic fashion during aging. (NeuroElectro data) (PubMed) Patrylo PR; Tyagi I; Willingham AL; Lee S; Williamson A Epilepsia 2007 10 1
GABA mediates the network activity-dependent facilitation of axonal outgrowth from the newborn granule cells in the early postnatal rat hippocampus. (NeuroElectro data) (PubMed) Lee H; Lee D; Park CH; Ho WK; Lee SH Eur. J. Neurosci. 2012 3 1
Experimental early-life febrile seizures induce changes in GABA(A) R-mediated neurotransmission in the dentate gyrus. (NeuroElectro data) (PubMed) Swijsen A; Avila A; Brône B; Janssen D; Hoogland G; Rigo JM Epilepsia 2012 3 1
Heterogeneous populations of cells mediate spontaneous synchronous bursting in the developing hippocampus through a frequency-dependent mechanism. (NeuroElectro data) (PubMed) Menendez de la Prida L; Sanchez-Andres JV Neuroscience 2000 20 5
Electrophysiological changes of CA3 neurons and dentate granule cells following transient forebrain ischemia. (NeuroElectro data) (PubMed) Howard EM; Gao TM; Pulsinelli WA; Xu ZC Brain Res. 1998 12 2
Electrophysiological characterization of granule cells in the dentate gyrus immediately after birth. (NeuroElectro data) (PubMed) Pedroni A; Minh do D; Mallamaci A; Cherubini E Front Cell Neurosci 2014 14 1
High temperatures alter physiological properties of pyramidal cells and inhibitory interneurons in hippocampus. (NeuroElectro data) (PubMed) Kim JA; Connors BW Front Cell Neurosci 2012 30 5
Competition from newborn granule cells does not drive axonal retraction of silenced old granule cells in the adult hippocampus. (NeuroElectro data) (PubMed) Lopez CM; Pelkey KA; Chittajallu R; Nakashiba T; Tóth K; Tonegawa S; McBain CJ Front Neural Circuits 2012 8 1
Molecular and functional characterization of GAD67-expressing, newborn granule cells in mouse dentate gyrus. (NeuroElectro data) (PubMed) Cabezas C; Irinopoulou T; Cauli B; Poncer JC Front Neural Circuits 2013 12 1
Preventing effect of L-type calcium channel blockade on electrophysiological alterations in dentate gyrus granule cells induced by entorhinal amyloid pathology. (NeuroElectro data) (PubMed) Pourbadie HG; Naderi N; Mehranfard N; Janahmadi M; Khodagholi F; Motamedi F PLoS ONE 2015 6 1
Distinct determinants of sparse activation during granule cell maturation. (NeuroElectro data) (PubMed) Dieni CV; Nietz AK; Panichi R; Wadiche JI; Overstreet-Wadiche L J. Neurosci. 2013 28 1
The endocannabinoid 2-arachidonoylglycerol negatively regulates habituation by suppressing excitatory recurrent network activity and reducing long-term potentiation in the dentate gyrus. (NeuroElectro data) (PubMed) Sugaya Y; Cagniard B; Yamazaki M; Sakimura K; Kano M J. Neurosci. 2013 6 2
Dendritic morphology, synaptic transmission, and activity of mature granule cells born following pilocarpine-induced status epilepticus in the rat. (NeuroElectro data) (PubMed) Gao F; Song X; Zhu D; Wang X; Hao A; Nadler JV; Zhan RZ Front Cell Neurosci 2015 8 1
Impaired firing properties of dentate granule neurons in an Alzheimer's disease animal model are rescued by PPARγ agonism. (NeuroElectro data) (PubMed) Nenov MN; Tempia F; Denner L; Dineley KT; Laezza F J. Neurophysiol. 2015 31 1
Intrinsic neurophysiological properties of hilar ectopic and normotopic dentate granule cells in human temporal lobe epilepsy and a rat model. (NeuroElectro data) (PubMed) Althaus AL; Sagher O; Parent JM; Murphy GG J. Neurophysiol. 2015 6 1
Intrinsic membrane properties determine hippocampal differential firing pattern in vivo in anesthetized rats. (NeuroElectro data) (PubMed) Kowalski J; Gan J; Jonas P; Pernía-Andrade AJ Hippocampus 2016 37 3
TWIK-1 contributes to the intrinsic excitability of dentate granule cells in mouse hippocampus. (NeuroElectro data) (PubMed) Yarishkin O; Lee da Y; Kim E; Cho CH; Choi JH; Lee CJ; Hwang EM; Park JY Mol Brain 2014 5 1

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