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Article: Rapid reversal of impaired inhibitory and excitatory transmission but not spine dysgenesis in a mouse model of mental retardation.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Powell AD; Gill KK; Saintot PP; Jiruska P; Chelly J; Billuart P; Jefferys JG
J. Physiol. (Lond.), 2012

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Dentate gyrus granule cell cell capacitance (pF) 93.3 ± 10.1 93.3 (pF) Data Table
Dentate gyrus granule cell fast AHP amplitude (mV) -4.1 ± 1.8 4.1 (mV) Data Table
Dentate gyrus granule cell firing frequency (Hz) 56.3 ± 7.0 56.3 (Hz) Data Table
Dentate gyrus granule cell input resistance (MΩ) 351.3 ± 39.8 351.3 (MΩ) Data Table
Dentate gyrus granule cell resting membrane potential (mV) -73.8 ± 2.4 -73.8 (mV) Data Table
Dentate gyrus granule cell slow AHP amplitude (mV) -3.7 ± 0.8 3.7 (mV) Data Table
Dentate gyrus granule cell spike half-width (ms) 1.55 ± 0.09 1.55 (ms) Data Table
Dentate gyrus granule cell spike threshold (mV) -37.3 ± 3.5 -37.3 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
RecTemp 29.0 - 31.0
AnimalAge 21.0 - 56.0
PrepType in vitro
ElectrodeType Patch-clamp
Species Mice
ExternalSolution 5.0
external_1_pH 7.4
external_1_Mg 1.0
external_1_Ca 2.0
external_1_Na 152.25
external_1_Cl 144.0
external_1_K 3.0
InternalSolution 5.0
internal_1_pH 7.3
internal_1_Mg 4.0
internal_1_Na 0.3
internal_1_Cl 139.0
internal_2_pH 7.3
internal_2_Mg 2.0
internal_2_Na 8.3
internal_2_Cl 8.0
JxnPotential Unreported
internal_0_pH 7.3
internal_0_Mg 2.0
internal_0_Na 8.3
internal_0_K 140.0
internal_0_GTP 0.3
internal_0_ATP 2.0
internal_0_HEPES 10.0
internal_0_Cl 8.0
external_0_pH 7.4
external_0_Mg 1.0
external_0_Na 152.25
external_0_K 3.0
external_0_Cl 144.0
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
10253 Rapid reversal of impaired inhibitory and excitatory transmission but not spine dysgenesis in a mouse model of mental retardation. Powell AD; Gill KK; Saintot PP; Jiruska P; Chelly J; Billuart P; Jefferys JG J. Physiol. (Lond.) 2012 True 8 Shreejoy Tripathy, James liu, Athanasios Kritharis, 2